Kao LP, Morad SAF, Davis TS, MacDougall MR, Kassai M, Abdelmageed N, Fox TE, Kester M, Loughran TP Jr, Abad JL, Fabrias G, Tan SF, Feith DJ, Claxton DF, Spiegel S, Fisher-Wellman KH, Cabot MC.
Chemotherapy selection pressure alters sphingolipid composition and mitochondrial bioenergetics in resistant HL-60 cells.
J Lipid Res. 2019 Sep;60(9):1590-1602. doi: 10.1194/jlr.RA119000251. Epub 2019 Jul 30. PubMed PMID: 31363040; PubMed Central PMCID: PMC6718434.
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Goldberg EJ, Buddo KA, McLaughlin KL, Fernandez RF, Pereyra AS, Psaltis CE, Lin CT, Hagen JT, Boykov IN, Nguyen TK, Gowdy KM, Ellis JM, Neufer PD, McClung JM, Fisher-Wellman KH.
Tissue-specific characterization of mitochondrial branched-chain keto acid oxidation using a multiplexed assay platform.
Biochem J. 2019 May 31;476(10):1521-1537. doi: 10.1042/BCJ20190182. PubMed PMID: 31092703.
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Douros JD, Niu J, Sdao S, Gregg T, Fisher-Wellman K, Bharadwaj M, Molina A, Arumugam R, Martin M, Petretto E, Merrins MJ, Herman MA, Tong J, Campbell J, D'Alessio D.
Sleeve gastrectomy rapidly enhances islet function independently of body weight.
JCI Insight. 2019 Mar 21;4(6). doi: 10.1172/jci.insight.126688. eCollection 2019 Mar 21. PubMed PMID: 30777938; PubMed Central PMCID: PMC6483064.
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Fisher-Wellman KH, Draper JA, Davidson MT, Williams AS, Narowski TM, Slentz DH, Ilkayeva OR, Stevens RD, Wagner GR, Najjar R, Hirschey MD, Thompson JW, Olson DP, Kelly DP, Koves TR, Grimsrud PA, Muoio DM.
Respiratory Phenomics across Multiple Models of Protein Hyperacylation in Cardiac Mitochondria Reveals a Marginal Impact on Bioenergetics.
Cell Rep. 2019 Feb 5;26(6):1557-1572.e8. doi: 10.1016/j.celrep.2019.01.057. PubMed PMID: 30726738; PubMed Central PMCID: PMC6478502.
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Fazakerley DJ, Chaudhuri R, Yang P, Maghzal GJ, Thomas KC, Krycer JR, Humphrey SJ, Parker BL, Fisher-Wellman KH, Meoli CC, Hoffman NJ, Diskin C, Burchfield JG, Cowley MJ, Kaplan W, Modrusan Z, Kolumam G, Yang JY, Chen DL, Samocha-Bonet D, Greenfield JR, Hoehn KL, Stocker R, James DE.
Mitochondrial CoQ deficiency is a common driver of mitochondrial oxidants and insulin resistance.
Elife. 2018 Feb 6;7. doi: 10.7554/eLife.32111. PubMed PMID: 29402381; PubMed Central PMCID: PMC5800848.
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Chaudhuri R, Krycer JR, Fazakerley DJ, Fisher-Wellman KH, Su Z, Hoehn KL, Yang JYH, Kuncic Z, Vafaee F, James DE.
The transcriptional response to oxidative stress is part of, but not sufficient for, insulin resistance in adipocytes.
Sci Rep. 2018 Jan 29;8(1):1774. doi: 10.1038/s41598-018-20104-x. PubMed PMID: 29379070; PubMed Central PMCID: PMC5789081.
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Stöckli J, Fisher-Wellman KH, Chaudhuri R, Zeng XY, Fazakerley DJ, Meoli CC, Thomas KC, Hoffman NJ, Mangiafico SP, Xirouchaki CE, Yang CH, Ilkayeva O, Wong K, Cooney GJ, Andrikopoulos S, Muoio DM, James DE.
Metabolomic analysis of insulin resistance across different mouse strains and diets.
J Biol Chem. 2017 Nov 24;292(47):19135-19145. doi: 10.1074/jbc.M117.818351. Epub 2017 Oct 5. PubMed PMID: 28982973; PubMed Central PMCID: PMC5702658.
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Anderson KA, Huynh FK, Fisher-Wellman K, Stuart JD, Peterson BS, Douros JD, Wagner GR, Thompson JW, Madsen AS, Green MF, Sivley RM, Ilkayeva OR, Stevens RD, Backos DS, Capra JA, Olsen CA, Campbell JE, Muoio DM, Grimsrud PA, Hirschey MD.
SIRT4 Is a Lysine Deacylase that Controls Leucine Metabolism and Insulin Secretion.
Cell Metab. 2017 Apr 4;25(4):838-855.e15. doi: 10.1016/j.cmet.2017.03.003. PubMed PMID: 28380376; PubMed Central PMCID: PMC5444661.
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Hoffman NJ, Parker BL, Chaudhuri R, Fisher-Wellman KH, Kleinert M, Humphrey SJ, Yang P, Holliday M, Trefely S, Fazakerley DJ, Stöckli J, Burchfield JG, Jensen TE, Jothi R, Kiens B, Wojtaszewski JF, Richter EA, James DE.
Global Phosphoproteomic Analysis of Human Skeletal Muscle Reveals a Network of Exercise-Regulated Kinases and AMPK Substrates.
Cell Metab. 2015 Nov 3;22(5):922-35. doi: 10.1016/j.cmet.2015.09.001. Epub 2015 Oct 1. PubMed PMID: 26437602; PubMed Central PMCID: PMC4635038.
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Tan SX, Fisher-Wellman KH, Fazakerley DJ, Ng Y, Pant H, Li J, Meoli CC, Coster AC, Stöckli J, James DE.
Selective insulin resistance in adipocytes.
J Biol Chem. 2015 May 1;290(18):11337-48. doi: 10.1074/jbc.M114.623686. Epub 2015 Feb 26. PubMed PMID: 25720492; PubMed Central PMCID: PMC4416839.
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Brown DA, Hale SL, Baines CP, del Rio CL, Hamlin RL, Yueyama Y, Kijtawornrat A, Yeh ST, Frasier CR, Stewart LM, Moukdar F, Shaikh SR, Fisher-Wellman KH, Neufer PD, Kloner RA.
Reduction of early reperfusion injury with the mitochondria-targeting peptide bendavia.
J Cardiovasc Pharmacol Ther. 2014 Jan;19(1):121-32. doi: 10.1177/1074248413508003. Epub 2013 Nov 28. PubMed PMID: 24288396; PubMed Central PMCID: PMC4103197.
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Brown DA, Hale SL, Baines CP, del Rio CL, Hamlin RL, Yueyama Y, Kijtawornrat A, Yeh ST, Frasier CR, Stewart LM, Moukdar F, Shaikh SR, Fisher-Wellman KH, Neufer PD, Kloner RA.
Reduction of early reperfusion injury with the mitochondria-targeting peptide bendavia.
J Cardiovasc Pharmacol Ther. 2014 Jan;19(1):121-32. doi: 10.1177/1074248413508003. Epub 2013 Nov 28. PubMed PMID: 24288396; PubMed Central PMCID: PMC4103197.
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